Cancer metastatic in bones. REVIEW-URI

The Second Edition expands on the original overview of bone cancer development physiology and pathophysiologywith key chapters from the first edition, and offers numerous new chapters describing the new concepts of bone cancer cancer metastatic in bones and therapy, for both primary bone tumors as well as bone metastases.

Each chapter has been written by internationally recognized specialists on the bone cancer microenvironment, bone metastases, osteoclast biology in bone cancer, proteomics, bone niche, circulating tumor cells, and clinical trials.

Given the global prevalence of breast and prostate cancers, knowledge of bone biology has become essential for everyone within the medical and cancer research communities.

Bone Cancer continues to offer the only translational reference to cover all aspects of primary bone cancer and bone metastases — from bench to bedside: development cellular and molecular mechanismsgenomic and proteomic analyses, clinical analyses histopathology, imaging, pain monitoringas well as new therapeutic approaches and clinical trials for primary bone tumors and bone metastases.