Protocolul de diagnostic pentru metastazele limfoganglionare laterocervicale cu punct de plecare neprecizat.
Source: Romanian Journal of Medical Practice. In patients with CUP, no established concept exists for the necessary diagnostic procedures.
In order to find the primary tumor, extensive diagnostic steps are generally recommended, however they are often not perform consistently. Panendoscopy under anesthesia with blind biopsies from nasopharynx, tongue base, tonsil and piriform sinus are generally used.
While the ability of CT to detect metastatic lymph nodes in head and neck tumors is quite acceptable, it is less so for correctly staging them, it is therefore necessary to look for other imaging tests that provide greater accuracy. However, false-positive results remain a limitation of the investigation.
Detection of the primary tumor has a key role in the management of patients with unknown primary tumors.
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