Chirurgia Bucur ; 5 : They are considered to be relatively rare tumors; however, more recent studies on NET epidemiology have demonstrated an increasing incidence and prevalence over the past 30 years. Aims: We intend to compare the strategy used in a real life clinical environment in the case of pancreatic neuroendocrine tumors, as opposed to an ideal model, as presented in literature.
Materials and methods: Our case series consist in 18 patients with neuroendocrine pancreatic tumors diagnosed and treated in the Surgery I department of Clinical Hospital Dr.
Recurrent Papillary Carcinoma stage III
Cantacuzino over a year period We made a retrospective analysis of these patients, of their diagnosis particularities and choice of treatment and a review of the literature. Results: Out of these 18 cases, 13 had functioning tumors 11 insulinomas and 2 gastrinomas and 5 non-functioning tumors.
Ann Anat ;Sep. Histologically, there are four types of fat tissue cells which are currently recognized white, brown, beige, and perivascular adipocytes. Therefore, in this study we are reviewing the most recent data regarding the origin, structure, and molecular mechanisms involved in the development of adipocytes. White adipocytes can store triglycerides as a consequence of lipogenesis, under the regulation of growth hormone or leptin and adiponectin, and release fatty acids resulted from lipolysis, under the regulation of the sympathetic nervous system, glucocorticoids, TNF-α, insulin, and natriuretic peptides.
Most of the tumors were located in the tail of the pancreas 12 cases the others were located in the body 1 cases and the head of the pancreas 5. Surgical papillary thyroid cancer with tall cell variant consisted in 10 enucleations 3 of them laparoscopic and 8 pancreatic resections, 2 of them associated with splenectomy and in one case a liver metastasectomy was also performed.
The mean follow-up was 12 months. No local or distant recurrences were found with one exception, one female which presented after one year with a cephalic pancreatic tumor that proved to be an adenocarcinoma.
Conclusions: Diagnosis of PNETs may be difficult even in the presence of a hormonal hypersecretion syndrome. Nuclear imaging with octreotide is useful for locating the tumor and also for the detectionof any possible occult tumors which cannot be identified through the use of conventional imaging.
All PNETs should be considered as potentially malignant, and the use of the term benign should be particularly avoided, which is why tumor grading based on the mitotic count and Ki index must be established for every case. Surgical treatment remains the papillary thyroid cancer with tall cell variant with curative potential.
Anca P. Stoian et al. The incidence of thyroid cancer is significantly different between male and female patients. Thyroid cancer is also the only form of cancer where age can be considered a staging variable.