In addition to tobacco and alcohol abuse, certain viruses have been associated with squamous cell carcinoma SCC of the head and neck, causing alterations in DNA.
Apasă pentru a vedea definiția originală «papillomavirus» în dicționarul Engleză dictionary. Apasă pentru a vedea traducerea automată a definiției în Română. Papillomaviridae Papillomaviridae Papillomaviridae este o veche familie taxonomică a virusurilor ADN ne-învelite, denumite în mod colectiv papilomavirusuri. S-au identificat câteva sute de specii de papilomavirusuri, denumite în mod tradițional "tipuri", infectând toate mamiferele inspectate cu atenție, dar și alte amniote, cum ar fi păsările, șerpii și broaștele țestoase. Infecția cu majoritatea tipurilor de papilomavirus, în funcție de tipul lor, este fie asimptomatică, fie cauzează tumori benigne mici, cunoscute sub numele de papilom sau negi.
It has been demonstrated that the human papillomavirus HPV type 16, a subtype of the human papillomavirus, is present in the oropharyngeal carcinomas of non-smokers patients inclusive. HPV-infected cells express some viral proteins encoded by genes called E6 and E7, and can inactivate p53 protein and the retinoblastoma-type protein RBP involved in the regulation of proliferation and cell death.
Materials and method. We present an immunohistochemical study conducted to identify significant tumour markers in tonsillar SCC. We present the statistically significant correlations between the presence of immunohistochemical papilloma of tonsil treatment and studied local recurrence, lymph node recurrence and risk of a second cancer in the aerodigestive upper tract. The demonstration of HPV in tonsillar tumour tissue requires in situ hybridization or polymerase chain reaction PCR for the evidence of viral genome included into the host cell.
Înțelesul "papillomavirus" în dicționarul Engleză
The practical implications of an etiologic role of HPV in head and neck cancer generally and in tonsillar SCC in particular remains in question and is in relate with prognosis, treatment and prevention. În afară de consumul de tutun şi abuzul de alcool, anumite virusuri au fost asociate cu carcinomul cu celule scuamoase CCS al papilloma of tonsil treatment şi gâtului, cauzând alterări la nivelul ADN-ului. Este dovedit că virusul papiloma uman HPVtipul 16, este prezent la nivelul carcinoamelor orofaringiene inclusiv în cazul nefumătorilor.
Но, безусловно, не стоит заранее предупреждать его о готовящемся побеге.
- Papiloma humano transmision
Celulele infectate cu HPV exprimă unele proteine virale codate de genele denumite E6 şi E7 şi pot inactiva proteina p53 şi proteina de tip retinoblastom RBP implicate în reglarea proliferării şi morţii celulare. Materiale şi metodă.
Prezentăm un studiu imunohistochimic realizat cu scopul de a identifica markeri tumorali semnificativi în CCS de amigdală.
Prezentăm corelaţiile semnificative statistic între prezenţa markerilor imunohistochimici şi recurenţa papilloma of tonsil treatment of tonsil treatment, recurenţa nodulilor limfatici şi riscul apariţiei unui al doilea cancer în tractul aerodigestiv superior.
Punerea în evidenţă papilloma of tonsil treatment HPV-ului în ţesutul tumoral amigdalian necesită hibridizare in situ şi reacţie de polimerizare în lanţ PCR pentru punerea în evidenţă a genomului viral conţinut în celula-gazdă. Implicaţiile practice ale unui rol etiologic al HPV-ului în cancerele de cap şi gât, în general, şi în CCS de amigdală, în particular, reprezintă un subiect în dezbatere, fiind în relaţie cu prognosticul, tratamentul şi prevenţia acestor tipuri de cancere.
Sinonimele și antonimele papillomavirus în dicționarul de sinonime Engleză
Cuvinte cheie carcinomul cu celule scuamoase de amigdală CCS Papilloma of tonsil treatment markeri tumorali Introduction The tonsillar squamous cell carcinoma SCC is becoming a public health problem because of its rising incidence in the last 20 years, in contrast to the decreasing incidence of carcinomas in other subsites of head and neck associated to the reduced prevalence of smoking. These tumours of oral cavity, oropharynx, larynx, hypopharynx and sinonasal region are linked by common characteristics, including a male predominant appearance in the 5th-6th decade of life, an important etiological link with tobacco, alcohol use or betel nut chewing, and a histopathological resemblance 1.
- Hpv males cure
Обладая невероятными познаниями, они преображали сушу и море.
Ричард завершил последние испытания как раз за день до встречи с Верховным Оптимизатором.
А как _ты_, Они встретились в середине комнаты и обнялись.
- Cancerul intestinului subtire simptome
Data regarding the epidemiology revealed that in Romania the oropharyngeal cancer represents 2. In France, during the last 30 years, the mortality in oral and oropharyngeal cancer increased by three times 1. As in cervical cancers, the oropharyngeal infection with HPV is a sexually transmitted disease which involves some particularities of sexual behaviour: a large number of vaginal sex partners, oral and anal sex. The recent increasing of OPSCC incidence may reflect the social changes regarding sexual behaviour in the modern world 6.
The anatomical sites preferred by HPV in oropharynx papilloma of tonsil treatment the tonsils and the tongue, because of the unique presence of transitional mucosa in oropharynx and particular in tonsillar tissue, which presents important histological similarities with the cervical mucosa.
Traducerea «papillomavirus» în 25 de limbi
Tonsillar epithelium invagination may favour virus capture papilloma of tonsil treatment promote its access to basal cells the only dividing cells in the epithelium. The tonsillar tissue could be a reservoir for HPV in the upper aero digestive tract.
We had two premises for our study on tonsillar cancers. The second consists in the fact that mutagens such as tobacco, alcohol and HPV viral oncogenes E6 and E7 induce dysfunctions of two major mechanisms of cellular cycle, which involves the p53 and RBP tumoral suppressor genes 2. Materials and method We made an immunohistochemical retrospective study between andaiming to identify any correlations between tumoral markers and the evolution and prognosis in tonsillar SCC.
Materials We studied 52 cases of patients diagnosed with tonsillar SCC.
We had a first group Group I with 25 cases, where the positive diagnose papilloma of tonsil treatment made by biopsy and these patients had radiotherapy as first curative method of treatment. We had a second group Group II with 27 cases, where the positive diagnose was made on surgical specimens and these patients had surgery as the first curative method of treatment.
The two groups were similar regarding age and gender distribution. The dilutions and markers specifications are revealed in Table 1. We also studied lymphocyte populations CD4, CD8, and populations of dendritic cells in tumour tissue.
Table 1. The dilutions and markers specifications For the immunohistochemical identification of tumoral antigens we used the three-stadial indirect method Avidine-Biotine-Peroxidase ABPafter Hsu and colab.
Results The gender repartition of cases was: 47 male cases and 5 female cases. The age repartition of cases was: two cases between years old, 14 cases between years old, 21 cases between years old, 10 cases between years old, and five cases between years old. The correlation coefficient between the two sets of data, corresponding to Group I and Group II, was 0. In both groups, we had 48 smoker patients, representing The patients who were both smokers and alcohol consumers represented We studied the tumoral markers on 52 cases of squamous cell carcinoma.
Thirty-eight cases were well differentiated carcinoma and papilloma of tonsil treatment cases were medium differentiated carcinoma. We present the results, that we considered immunohistochemically valid and statistically significant Table 2.
Table 2. The distribution of tumoral markers in specimens of SCC studied We realised a correlation between the presence of the tumoral marker of a certain type positive and slowly positive results and the post-therapeutic evolution — local recurrence, nodal relapse, the papilloma of tonsil treatment of second cancers in upper aerodigestive upper ways and distance metastases. We have had patients who had more than one recurrence in the same time.
А знаешь, - объявил он, - наша внучка - просто чудо. - Я тоже так считаю, - усмехнулась Николь. - Увы, мы с тобой оба не можем судить объективно.
Our purpose was to identify the correlations between markers of evolution and prognosis in tonsillar SCC. Our results indicate p53 protein and Does hpv virus cause acne protein as tumoral markers of unfavourable prognosis for post-therapeutic evolution in tonsillar SCC.
PAPILLOMAVIRUS - Definiția și sinonimele papillomavirus în dicționarul Engleză
For TGFa, we can make papilloma of tonsil treatment correlation between its level in tumoral tissue and the risk of loco-regional relapse. For the HPV identification in tumoral tissue, we used the identification of capsid p16 protein, so we cannot make definitive conclusions referring at the presence or papilloma of tonsil treatment of HPV in the tumoral tissue for patients with tonsillar SCC.
But we realised a correlation between the presence of HPV and the type of post-therapeutic evolution Figures Figure 1.
"О Боже, - вдруг подумала .
Тут началось настоящее столпотворение.
The presence of RBP protein 48 positive and slowly positive cases was associated with local recurrence in 29 cases The presence papilloma of tonsil treatment TGF protein 41 positive and slowly positive cases was associated with local recurrence in 18 cases The presence of HPV capsid protein 14 positive cases was associated with local recurrence in nine cases Figure 6.
Tumoral markers in evolution of tonsillar SCC result of our retrospective study From our data, we can certify as prognostic factors in tonsillar SCC: T stage, N stage, performing or not an elective type of clinical negative neck N0, type of neck dissection, the total dose of papilloma of tonsil treatment. We cannot make papilloma of tonsil treatment significant conclusions referring to the HPV presence in tumoral tissue in tonsillar SCC and long-term prognosis.
Demonstrating the presence of HPV in tonsillar tumoral tissue imposes hybridisation in situ or polymerase chain reaction PCR.
Discussion Slaughter et al.
They explained the greater risk for multiple primary cancers 8. Tobacco and alcohol abuse increase the risk for a second cancer development in patients with oropharyngeal SCC. Tobacco and alcohol abuse are associated with mutations of the p53 protein in patients with OFSCC, being important factors in the molecular progression through carcinogenesis 9.
Many clinical studies searched for the p53 protein mutations on surgical specimens from patients with OFSCC. The patients with surgical positive edges for p53 protein mutations have a higher risk of local relapse
Поинтересовалась Николь, глядя на уставленный едой стол посреди комнаты. - Пакует вещи, - проговорила Элли. - К тому же, она решила, что ей не стоит присутствовать при нашей беседе. - Итак, нас ждет еще одно потрясение.