Uterine cancer in elderly


Approximately one-quarter of these cancers occur in countries with low socio-economic levels where food deficiencies are simptome ca ai paraziti intestinali in etiology by the imbalance between physical activity and energy intake, while high sugar and fat content are the main factors incriminated in developed countries where a third of the most common cancers occur.

The relationship between diet and cancer risk is complex. Thermal food uterine cancer in elderly can result in carcinogenic byproducts.

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For instance, frying or uterine cancer in elderly meat can lead to the formation of polycyclic aromatic hydrocarbons such as benzopyrene.

Smoked meat and smoked fish consumption has been linked to gastric cancer in countries with high intake, such as Japan. Some vegetables, such as celery, endives, cabbage, spinach or turnips, have a high nitrate content, especially if they are stored for more than two days, if they undergo thermal processing or if they are combined with animal proteins. As nitrates change to nitrosamines, the carcinogenic potential of these types of food increases. Diet can also act as a protection against cancer.

A high intake of fruits and vegetables that contain large amounts of fibers has been often associated with a decreased colon cancer risk. Similar associations have been noted for gastric cancer and for other epithelial malignancies such as lung, pharynx, larynx, esophageal and breast cancer.

Consuming large amounts of food that contain phytoestrogens selective estrogen modulators may contribute to primary and secondary prophylaxis of endocrine-dependent cancers.

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The protective effect against cancer found for both fruits and vegetables is most likely due to a high content of vegetable fibers, specific vitamins and certain bioactive compounds such as carotene found in red vegetablesfolates found in green vegetablesglucosinolates brassica and alkyl sulfates garlic. The link between cancer and diet is as complex as neoplastic disease itself. Current studies indicate that certain foods and nutrients can help prevent or, on the contrary, develop certain types of cancer.

For the other risk factors we have the possibility to change them, including diet. Keywords diet, cancer, prophylaxis Rezumat Factorii alimentari joacă un rol complex în etiopatogeneza cancerelor umane.

Aproximativ un sfert din aceste tipuri de cancer apar în ţările cu un nivel socioeconomic scăzut, unde deficienţele alimentare sunt implicate în etiologie prin dezechilibrul dintre activitatea fizică şi consumul de energie, în timp ce conţinutul ridicat de zahăr şi grăsimi este principalul factor incriminat în ţările dezvoltate unde apar o treime din cele mai frecvente tipuri de cancer.

Relaţia dintre dietă şi riscul de cancer este complexă. Procesarea termică a unor alimente poate avea london cancer sarcoma guidelines rezultat produse secundare cancerigene. De exemplu, carnea prăjită sau afumată poate duce la formarea uterine cancer in elderly hidrocarburi aromatice policiclice, cum ar fi benzopiranul.

Consumul uterine cancer in elderly de peşte şi carne afumată a fost asociat cu cancerul gastric în unele ţări, cum ar fi Japonia. Unele legume, precum ţelina, andivele, varza, spanacul sau strugurii, au un conţinut ridicat de nitraţi, mai ales uterine cancer in elderly sunt depozitate mai mult de două zile, dacă sunt supuse procesării termice sau dacă sunt combinate cu proteine animale.

Pe uterine cancer in elderly ce uterine cancer in elderly se transformă în nitrozamine, creşte potenţialul carcinogen al acestor tipuri de alimente.

Dieta poate acţiona şi ca factor de protecţie împotriva cancerului. Un aport ridicat de fructe şi legume care conţin cantităţi mari de fibre a fost deseori asociat cu un risc scăzut de cancer de colon. Asociaţii similare au fost observate pentru cancerul gastric şi pentru alte afecţiuni maligne epiteliale, cum ar fi cancerul pulmonar, de faringe, de laringe, cancerul esofagian şi cel de sân.

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Consumul unor cantităţi mari de alimente care conţin fitoestrogeni modulatori selectivi ai estrogenului poate contribui la profilaxia primară şi secundară a cancerelor endocrin-dependente. Efectul protector împotriva cancerului, constatat atât pentru fructe, uterine cancer in elderly şi pentru legume, este cel mai probabil datorat unui conţinut ridicat de fibre vegetale, vitamine şi anumiţi compuşi bioactivi, cum ar fi carotenul aflat în legume roşiifolaţii din legumele verziglucozinolatul Brassica şi sulfatul de alchil usturoi.

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Legătura dintre cancer şi dietă este la fel de complexă ca şi boala neoplazică. Studiile actuale indică faptul că anumite alimente şi substanţe nutritive pot preveni sau, dimpotrivă, pot duce la dezvoltarea unor tipuri de cancer. Deşi există mulţi factori care cresc riscul de uterine cancer in elderly şi care nu pot fi schimbaţi cum ar fi genele şi mediulexistă şi alţii care pot fi controlaţi. Pentru ceilalţi factori de risc, avem posibilitatea de a-i schimba, inclusiv dieta. Cuvinte cheie dietă cancer profilaxie Nutrition-related factors play a complex role in the etiopathogenesis of human cancers.

About a quarter of these cancers occur in countries with low socioeconomic levels, where nutritional deficiencies are involved in etiology via imbalance between physical activity and energy intake, while high sugar and fat content are the main factors incriminated in developed countries where a third of the uterine cancer in elderly common cancers occur 1.

There are numerous data in favor of the idea that diet is a factor involved in the etiology of some cancers such as colon, stomach, pancreas, breast, ovary, uterus, prostate cancer. Several nutritional factor assumptions have been formulated to explain variations in the incidence of a particular neoplasm in different countries.

For example, consumption of smoked fish and smoked meat in Japan has been incriminated in the development of stomach cancer.

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  4. Agenda Conferinta Snomr | Melanoma | Oncology
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Nutrition can intervene in carcinogenesis process in circumstances such as: a. Providing a source of carcinogens or procarcinogens: foods containing carcinogenic substances or these may occur in the process of food processing or preservation.

Traducere "prostatic" în engleză

Encouraging the formation of carcinogenic substances: nitrates and nitrites, whose concentration can be elevated in some foods or drinking water, are transformed into nitrosamines.

Changing the effects of carcinogens: nutrition can play a protective role against carcinogens through fiber content, vitamins and antioxidants vitamins C, E and A, coenzyme Q10, melatonin, selenium, zinc. Selenium and vitamin E reduce the risk of prostate cancer. A diet rich in dietary fibers lowers the risk of colon, oral cavity, esophagus, stomach and lung cancers.

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A number of studies have suggested the protective effect of folic acid in reducing the risk of colon cancer. This effect can be explained by two theories: 1 the synthesis of radicals, donors of methyl complications of enterobiasis mediated by folate with methylation of DNA and regulation of gene expression; 2 there is a conversion of uracil to thiamine facilitated by folate, a mechanism involved in DNA repair 3.

Epidemiological data suggest that increased consumption of fat, protein, salt and a diet with low dietary fibers content USA, Western Europe are associated with an increased uterine cancer in elderly of colon cancer. The incidence of breast cancer is also high in countries where there is an increased consumption of saturated fats USA, Scandinavia.

The incidence of breast cancer in descendants of Japanese emigrants in the USA is as high as that of the American native population and much higher than that of Japanese residents, suggesting an important role in the diet 3.

In the process of preparing food by thermal processing, substances with a carcinogenic potential may result. Thus, benzopyrene and other aromatic polycyclic hydrocarbons may result uterine cancer in elderly the process of thermal processing pyrolysis of foods, for example, when the meat is roasted or smoked.

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Vegetables such as celery, endive, cabbage, spinach, kohlrabi contain large quantities of nitrates, especially if they are preserved for more than two days, if they are thermally prepared or combined with proteins, resulting in nitrosamines that have carcinogenic potential.

A number of substances such as preservatives or those intended to give color, taste, flavor or a certain consistency can cause potentially mutagenic effects, which is why some of these have been removed from uterine cancer in elderly market. For example, an increased content of saccharin determines bladder cancer in mice.

uterine cancer in elderly

There is uterine cancer in elderly clear epidemiological evidence in humans concerning the involvement of saccharin in the etiology of cancers. The nitrite or nitrate content nitrates can be reduced to nitrite in the gastrointestinal tract via the intervention of Helicobacter pylori of foods, and especially of meat, is another controversial topic. The fact that nitrites combine with secondary amines to form nitrosamines in the gastrointestinal tract is an essential argument for diminishing the consumption of uterine cancer in elderly as food additives 3,4.

The factors in the diet can also play a protective role. Thus, increased consumption of vegetables and fruits with uterine cancer in elderly fiber content has been consistently associated with a low risk of colon cancer.

Such arguments are also available for stomach cancers and other epithelial cancers such as lung, pharynx, uterine cancer in elderly, esophagus and breast cancers 3,4.

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It has been shown that strategies including uterine cancer in elderly modification involving estrogen modulators selective estrogen modulators such as phytoestrogens can provide effective strategies for the prevention of cancers mediated by endocrine mechanisms. Aflatoxin — a mycotoxin of Aspergillus flavus and A.

Doripenem penetrates well into several body fluids and tissues, such as uterine tissue, retroperitoneal fluid, prostatic tissue, gallbladder tissue and urine. Oxibutinina poate accentua uterine cancer in elderly de hipertiroidie, boal cardiac coronarian, insuficien cardiac congestiv, aritmii cardiace, tahicardie, hipertensiune i hipertrofie prostatic. Oxybutynin may exacerbate the symptoms of hyperthyroidism, coronary heart disease, congestive heart failure, cardiac arrhythmias, tachycardia, hypertension and prostatic hypertrophy În stadiile incipiente, adenocarcinomul prostatic este limitat la glandă.

The carcinogenic role of the hepatitis B and C viruses, as well as the presence of aflatoxin in food is correlated with the increased incidence of liver cancer in Asian and African rice-consuming countries stored under humid conditions, rice is contaminated with the Aspergillus flavus uterine cancer in elderly which secretes aflatoxin, a strong carcinogen involved in hepatocarcinoma etiopathogenesis 3,4.

Nutrition is a factor involved in the etiology of cancers such as colon, stomach, pancreas, breast, ovary, uterus, prostate cancers.

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Several nutritional factor assumptions have been formulated to explain the variations in the incidence of a particular neoplasm in different countries.

Some substances xenobiotics from food have uterine cancer in elderly associated with cancers, such as: increased fat consumption uterine cancer in elderly, prostate, endometrium and breast cancers ; polycyclic amines identified in well roasted meat have been involved in the development of gastric, colorectal, pancreatic and breast cancers; high calorie diets breast, endometrium, colon, prostate and gallbladder cancers ; animal uterine cancer in elderly, particularly red meat breast, endometrial and colon cancers ; alcohol, particularly in smokers cancers of the oral cavity, pharynx, larynx, esophagus and liver ; salted diets with smoked foods esophagus and stomach cancers ; nitrates and food additives intestinal cancer 4,5.

Obesity After reviewing all epidemiological studies in the last 30 years, The International Agency for Research on Cancer IARC concludes that obesity represents a causal link for various forms of cancer. The association between obesity and various cancers is complex 6.

The weight gain with every 5 kg increases the relative risk of developing breast cancer in postmenopausal women by 1. Overweight is one of the most important risk factors for cancers such as colon, breast after menopauseendometrium, esophagus adenocarcinomapancreas, and kidney cancer; most likely, for gallbladder cancer also 2,6.

Typical cancers in relationship to obesity are: a. Endometrial cancer — there uterine cancer in elderly a strong correlation between obesity and uterine cancer. So the risk of endometrial cancer in women with a weight gain of 20 kg after the age of 18 is 5 times higher.

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Both obesity and weight gain are associated with an increased risk of endometrial cancer. Colon cancer — the incidence of colon cancer increases in obese people. Renal carcinoma — obesity has an unexplained mechanism of increasing renal cancer, especially in women.

Esophageal cancer of the adenocarcinoma type — obesity is considered to increase uterine cancer in elderly risk of esophageal adenocarcinoma, with the increase in the prevalence of gastroesophageal reflux and the consecutive development of the Barett esophagus metaplastic precursor lesion of adenocarcinomas.

Some studies have shown that obesity contributes to the increase of esophageal uterine cancer in elderly independent of reflux disease. Other cancers that associate a lower risk with obesity are: pancreatic cancer it doubles the riskhepatocellular carcinoma, cardial gastric cancer due to gastro­esophageal reflux with Barett metaplasiaovarian and cervical cancer limited uterine cancer in elderly and lymphomas; further studies are needed to fully define these relationships 4.

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Obesity has been associated with the improvement of results in male patients with metastatic malignant melanoma treated with targeted molecular medication dabarfenib and trametinib, or vemurafenib and cobinetinib and immunotherapy nivolumab, pembrolizumab or atezolizumabbut not chemotherapy dacarbazine 9. The pathophysiological mechanisms by which obesity increases the risk of developing cancers are poorly understood.

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There is evidence that associates the physical inactivity and obesity with an increased uterine cancer in elderly of developing colon cancer. Several studies suggest that the association between lifestyle factors and colon cancer is mediated by hyperinsulinemia and insulin resistance via the insulin-like growth factor IGF 6,7. Increased plasma glucose level and type 2 diabetes are also recognized as risk factors for colon cancer.

Two main mechanisms are incriminated: endocrine disturbances such as the installation of insulin resistance; metabolic changes metabolic X syndrome 2,6. An increase in these cancers is estimated due to the dramatic increase in BMI in the population. Physical activity Optimal physical activity is relevant in the primary and secondary prevention of colorectal and breast cancers.

Independent of other factors, uterine cancer in elderly activity reduces the risk of colorectal cancers and protects against postmenopausal breast cancers and endometrial cancer. The mechanism is not elucidated, but it is believed that the weight loss affects sex hormones and specific endogenous growth factors.