Papillomaviruses,

Department of Ophthalmology, Grigore T.

E-mail: moc. We report the detection of HPV 52 in a sample papillomaviruses from a papillomaviruses patient with squamous cell carcinoma positiva papillomavirus the conjunctiva papillomaviruses the left eye.

The method used papillomaviruses the detection of HPV was real time polymerase chain reaction. The evolution was favorable after surgical removal of papillomaviruses tumor and the patient was explained that long-term follow-up is essential to avoid recurrence.

Keywords: Conjunctiva, eye, human papillomavirus 52, real time polymerase papillomaviruses reaction, squamous cell carcinoma Human papillomavirus HPV papillomaviruses is strongly associated with papillomaviruses tumors cervix, penis, vulva, vagina, anushead and neck cancers oral cavity, esophagus, larynxand nonmelanoma skin cancers squamous and basal cell carcinoma.

The association between HPV infection and eye tumors is little explored territory.

Di Girolamo brings papillomaviruses a two-hit theory that explains cancerogenesis in OSSN: The meaning of helminth hit is mediated by ultraviolet radiation exposure that causes genetic alteration and the second hit is mediated papillomaviruses HPV infection in the susceptible cells.

Case Report We present a unique case of squamous cell carcinoma of the conjunctiva examined and treated in June The year-old papillomaviruses presented at the Ophthalmology Department for mild stinging papillomaviruses and redness in the left eye for almost 1-year and a half.

He has been treated for the last 2 months with dexamethasone eye drops for scleritis by another ophthalmologist.

The patient admits being a heavy smoker for almost 30 years and that in his free time he practices agriculture without using papillomaviruses.

All other ophthalmological findings were normal. papillomaviruses

Human papillomavirus 52 positive squamous cell carcinoma of the conjunctiva

Conjunctival culture was performed before surgery, and no bacterial infection was found. The CT scan papillomaviruses the head and neck showed no signs of tumor invasion of the orbit or the lymph nodes.

The limbic lesion papillomaviruses removed surgically with 2 mm margin of normal tissue and papillomaviruses of the adjacent sclera was done. At the end, the remaining papillomaviruses defect was restored using a supero-nasal conjunctiva graft fixed in position with interrupted and surjet The excised tumor was cut into 2 fragments: One for pathology papillomaviruses in papillomaviruses and one for Papillomaviruses genotyping preserved in Cobas polymerase chain reaction PCR solution and refrigerated at 4°C until processing.

Histopathology exam showed a moderate differentiated keratinized squamous cell carcinoma of the conjunctiva without koilocytosis [Figs.